How Safe Is SADI Surgery in the Short Term After the Operation?

A 2026 study found that SADI-S, a weight loss surgery combining a sleeve gastrectomy with a bowel bypass, can be performed with a low rate of short term complications, even in patients with a high body weight or those having a repeat procedure.
Who Was Studied and How the Research Was Done
The study included 520 adults who had SADI-S at 15 accredited bariatric surgery centres across Mexico between January 2019 and April 2025. Most participants were women, with a median age of 46 years. Researchers reviewed clinical records to look at what complications occurred and which factors were linked to poorer outcomes.
What the Researchers Found
Postoperative complications occurred in about 1 in 40 patients (2.5%), and there were no deaths recorded in the group. Around 1 in 4 patients were having a revisional procedure, meaning a second or corrective weight loss surgery, and their outcomes were comparable to those having SADI-S for the first time. Longer operating time and greater blood loss during surgery were associated with a higher chance of complications.
What This Study Does and Does Not Tell Us
The findings suggest that experienced bariatric surgeons can perform SADI-S with acceptable short term safety, including in higher risk cases. Because this was a retrospective study from one country, the results may not apply to all settings or populations, and individual outcomes will always vary.
About this research: Perioperative Outcomes Following Single Anastomosis Duodeno Ileal Bypass with Sleeve Gastrectomy (SADI S): Analysis of a National Multicenter Mexican Cohort, Obesity Surgery, 2026. Read the study summary
More about this procedure is on our SADI page. If you are considering your options, call us on (03) 9760 2777 or request an appointment through our website.